Seneca (Noun) — Roman statesman and philosopher who was an advisor to Nero; his nine extant tragedies are modelled on Greek tragedies (circa 4 BC - 65 AD).
Seneca (Noun) — The Iroquoian language spoken by the Seneca.
Seneca (Noun) — A member of the Iroquoian people formerly living in New York State south of Lake Ontario.